Mucous and salivary gland tumours.

by Sameer Rafla-Demetrious

Publisher: Thomas in Springfield, Ill

Written in English
Published: Pages: 283 Downloads: 963
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  • Salivary glands -- Tumors

Edition Notes

SeriesAmerican lecture series, publication no. 758. A monograph in the Bannerstone division of American lectures in radiation therapy
LC ClassificationsRC280 S3 R3
The Physical Object
Number of Pages283
ID Numbers
Open LibraryOL19972760M

Mucous and serous glands in the respiratory tract rarely produce tumours that are histologically identical to tumours derived from the salivary glands of the head and neck. Electron microscopic and immunohistochemical studies confirm the similarity between tumours in these two locations. 45% of tumours in submandibular gland are malignant. 50% of tumours in minor salivary gland are malignant and 50% adenoid cystic carcinoma. 60% of salivary neoplasms in children are malignant. Epidemiology. Sex Benign F>M Malignant M=F. Distribution overall Parotid 80%. Wnt/b-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours Peter Wend1,7, Liang Fang1, Qionghua Zhu1,Jo¨rg H Schipper2, Christoph Loddenkemper3, Frauke Kosel1, Volker Brinkmann4, Klaus Eckert1, Simone Hindersin2, Jane D Holland1, Stephan Lehr5, Michael Kahn6, Ulrike Ziebold1,8 and Walter Birchmeier1,8,* 1Max-Delbrueck Center Cited by:   Most (~70%) salivary gland tumors originate in the parotid gland, with the bulk of the remainder arising in the submandibular gland (~8%) and in the minor salivary glands (~22%). [ 1, 2 ] Although 75% of parotid gland tumors are benign, slightly more than 50% of tumors of the submandibular gland and % of minor salivary gland tumors are.

Emphasizing changes in the field of salivary gland disease, including coverage of neoplastic and non-neoplastic areas, this text presents a view of salivary gland disease in a manner that is readily usable as a reference by surgical pathologists and clinicians. As many pathologists have limited opportunity for experience with problems of salivary glands, and because the involved .   • The UCLA experience with minor salivary gland tumors of the lip is presented and contrasted with that of the literature. The incidence of benign to malignant tumors of the lip does not follow the inverse relationship stated in the axiom that the smaller the salivary gland the greater the probability that a developing tumor will be by: People with salivary gland cancer may have questions about their prognosis and survival. Prognosis and survival depend on many factors. Only a doctor familiar with a person’s medical history, type of cancer, stage, characteristics of the cancer, treatments chosen and response to treatment can put all of this information together with survival statistics to arrive at a prognosis. • salivary gland tumors are rare in children; 50% are malignant most are mucoepidermoid carcinoma SALIVARY GLAND NEOPLASMS General Features Site Frequency Proportion malignant Parotid 65% 25% Submandibular 10% 40% Sublingual File Size: 3MB.

Sep1;13(9):E Tumors of minor salivary glands E Introduction Salivary gland neoplasms represent less than 1% of all tumors, and % of all head and neck neoplasms. Minor salivary gland tumors (MSGTs) are infrequent, accounting for % of all salivary neoplasms, and are fundamentally located in the palate (50%), lips (15%).

Mucous and salivary gland tumours. by Sameer Rafla-Demetrious Download PDF EPUB FB2

Additional Physical Format: Online version: Rafla, Sameer. Mucous and salivary gland tumours. Springfield, Ill., Thomas [] (OCoLC) Online version.

To receive access to the full text of freely available articles, alerts, and more. You will be directed to to complete your registration. This monograph is based on a detailed review of more than 1, aspiration cytology biopsies of salivary gland tumors, including even rare entities, which were collected over a period of 45 years at the Institut Curie and correlated with histopathological diagnoses according to the most recent classifications (WHO and AFIP).

Review of such a large series of cases has allowed the. XII OCTOBER NO. 4 MUCOUS GLAND TUMOURS* A. THACKRAY, M.D. Bland-Sutton Institute of Pathology, The Middlesex Hospital, London, W. 1 Mucous gland tumours may arise in connection with any of the three main groups of glands--the major salivary glands, the minor salivary glands and the mucous glands of the respiratory by: 1.

About 85% of salivary gland tumors occur in the parotid glands, followed by the submandibular and minor salivary glands, and about 1% occur in the sublingual glands. About 75 to 80% are benign, slow-growing, movable, painless, usually solitary Mucous and salivary gland tumours.

book beneath normal skin or mucosa. Worldwide annual incidence of salivary gland tumours varies from to % per 1 lakh population. 1 Overall about % of head and neck cancers are salivary gland neoplasms. salivary glandtumours A number of biological main features, of importance for the present study, from the recent Scandinavian investigations into mucous and salivary gland tumours will be briefly summed up.

The mucous and salivary gland tumours belong to the com-paratively rare forms. Theyoccur mostoften in the large salivaryCited by: Most salivary gland tumors are benign and occur in the parotid glands.

A painless salivary mass is the most common sign and is evaluated by fine-needle aspiration biopsy. Imaging with CT and MRI can be helpful. For malignant tumors, treatment is with excision and radiation. Long-term results are related to the grade of the cancer. Salivary gland tumours present a diverse range of histological and clinical behaviours.

The rarity of these tumours combined with the diverse histology means that there is a lack of studies that can be used to provide strong recommendations for Mucous and salivary gland tumours. book individual histologic subtype of Cited by: Salivary secretions and structure.

Saliva consists of two fluids, mucous and serous. Mucous. Mucous (slime) is a saccharide glycoprotein called water it makes the slippery lubricant used in many parts of the body, where it lines the moving parts, surfaces and tubes. Here it lubricates the mouth, throat and alimentary canal.

The mucous also has antiseptic. The Lancet LEADING ARTICLES Salivary-gland Tumours SALIVARY-GLAND tumours are relatively uncommon, but they have occasioned much interest and debate because of their great variability in structure and behaviour.

It is only in the past two or three decades, following technical advances in the surgery of the major salivary glands, that. These tumours can be benign or malignant, with parotid tumours less likely to be malignant than those in the submandibular, sublingual or minor salivary glands. Epidemiology.

Salivary gland tumours have an incidence of 1 inThey are slightly more common in women than in men and more common in adults. Salivary gland tumours most often present as painless enlarging masses.

Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical Cited by: that 26% of minor salivary gland tumours were poly-morphous low grade adenocarcinomas, and in an African population, Van Heerden and Raubenheimer () found it to be the most common intraoral salivaryglandmalignancy.

Approaches to the diagnosis of salivary gland tumours Salivary tumours are a particular challenge to the diagnostic pathologist.

67 Abstract: The aims of this study were to determine the incidence of malignant salivary gland tumors (MSGTs) in a specific in Spanish Mediterranean population, evaluate oncological outcomes, and. Here you can find more information on the different types of salivary gland cancers. Mucoepidermoid Carcinoma.

Mucoepidermoid carcinoma is the most common type of salivary gland cancer. More than 30 percent of salivary gland cancers are thought to be this type.

Cancers that develop here often form tiny mucous-filled cysts. GODWIN JT. Benign lymphoepithelial lesion of the parotid gland adenolymphoma, chronic inflammation, lymphoepithelioma, lymphocytic tumor, Mikulicz disease.

Cancer. Nov; 5 (6)– GODWIN JT, FOOTE FW, Jr, FRAZELL EL. Acinic cell adenocarcinoma of the parotid gland; report of twenty-seven cases.

Am J Pathol. May-Jun; 30 (3) Cited by: 8. The salivary glands in mammals are exocrine glands that produce saliva through a system of have three paired major salivary glands (parotid, submandibular, and sublingual) as well as hundreds of minor salivary ry glands can be classified as serous, mucous or seromucous (mixed).

In serous secretions, the main type of protein secreted is alpha MeSH: D   eBook is an electronic version of a traditional print book THIS can be read by using a personal computer or by using an eBook reader. (An eBook reader can be a software application for use on a computer such as Microsoft's free Reader application, or a book-sized computer THIS is used solely as a reading device such as Nuvomedia's Rocket eBook.).

Although almost 40 histologic types of epithelial tumors of the salivary glands exist, some are exceedingly rare and may be the subject of only a few case reports.[1,11] The most common benign major and minor salivary gland tumor is the pleomorphic adenoma, which comprises about 50% of all salivary gland tumors and 65% of parotid gland tumors.

The salivary gland section in the 4th edition of the World Health Organization classification of head and neck tumors features the description and inclusion of several entities, the most significant of which is represented by (mammary analogue) secretory carcinoma. This entity was extracted mainly from acinic cell carcinoma based on recapitulation of breast Cited by:   Mucous: Minor salivary glands.

Parotid gland: Largest salivary gland 60 to 65% of total saliva. Pyramidal in shape. Weighs between 14 & 28g. Superficial portion of gland is located subcutaneously, in front of the external ear & deeper portion lies behind ramus of mandible.

Associated with facial nerve. Salivary gland tumors (SGTs) are rare neoplasms accounting for cases per people. Malignant SGTs represent 6% of head and neck cancers and % of all cancers in the US.

Still in the US, carcinomas of the major salivary. Salivary gland tumours. A review of cases with particular reference to histological types, site, age and sex distribution.

J Pathol ; 51 – Author: Sherif Said, Robert O. Greer, Robert E. Marx. Neoplasms. Tumors of the salivary gland are relatively uncommon, constituting approximately 2% of head and neck neoplasms; most (80%) occur in the parotid gland, and most of those are benign.

1 Although benign and malignant salivary gland neoplasms do not usually present with pain, pain can be associated with a neoplasm secondary to suppuration, hemorrhage into a.

Pleomorphic adenoma is the most frequent benign tumour of both the major (extra-oral) and the minor (intra-oral) salivary glands.

80% of the cases occur in the parotid gland (mixed parotid tumour). This tumour occurs most commonly in the fourth to fifth decade, with a prevalence in females.

Clinically, there is a slowly growing swelling which may reach a significant size. Salivary gland neoplasms make up 6% of all head and neck tumors.

[] The incidence of salivary gland neoplasms as a whole is approximately cases perindividuals in the United States, with malignant neoplasms accounting for cases per[] Mortality from malignant salivary gland neoplasms varies by stage and pathology, but the.

Salivary gland, any of the organs that secrete saliva, a substance that moistens and softens food, into the oral cavity of vertebrates. Salivary glands may be predominantly serous, mucous, or mixed in secretion. Mucus is a thick, clear, and somewhat slimy substance.

Serous secretion is. SALIVARY GLAND tumors are a comparatively rare disorder, accounting for only 1% of all neoplasms of the head and neck region.

1 Further complicating the analysis of these tumors in the pediatric population is that fewer than 5% of all salivary tumors occur in patients younger than 16 years. 2 Not all masses arising in a salivary gland region represent tumors of Cited by: Classification of salivary gland tumours - a brief histopathological review R.H.W.

Simpson Department of Histopathology, Postgraduate Medical School, University of Exeter, Exeter, England Summary. Tumours of the salivary glands display a wide variety of histological appearances, and vary inFile Size: 6MB.

Classification difficult because most tumors arise from or differentiate to epithelial or myoepithelial cells, which can undergo various metaplastic changes (oncocytic, chondroid, squamous, sebaceous).-most common MALIGNANT SALIVARY GLAND NEOPLASM-most common SALIVARY MALIGNANCY in CHILDREN-PAROTID GLAND most common-BLUE pigmented mass-low, intermediate, high grades-mixture mucous producing cells and squamous (epidermoid) cells-moderately well differentiated tumor with DUCTAL and CYSTIC spaces surrounded by .References.

1 Diagnostic histopathology of tumors. Edited by CDM Fletcher. 2nd edition. Churchill Livingstone. Page 2 Meer S,Altini M.

CK7+/CK immunoexpression profile is typical of salivary gland neoplasia. Histopathology ; 3 Nikitakis NG, Tosios KI, Papanikolaou VS, et al.

Immunohistochemical expression of cytokeratins 7 and 20 in malignant salivary .